Benutzer: Gast  Login
Mehr Felder
Einfache Suche
Titel:

A question of timing: emerging links between transcription and replication.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Autor(en):
Schwaiger, M; Schübeler, D
Abstract:
The coordination of transcription and timing of DNA replication during the S phase of the cell cycle has recently been studied chromosome-wide in high resolution. This revealed that in the complex genome of higher eukaryotes actively transcribed genes are more likely to replicate early in S phase. Dynamic changes in chromatin structure and nuclear organization appear to provide the underlying mechanism to link transcription and replication. A possible evolutionary benefit for this connection mig...     »
Zeitschriftentitel:
Curr Opin Genet Dev
Jahr:
2006
Band / Volume:
16
Heft / Issue:
2
Seitenangaben Beitrag:
177-83
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.gde.2006.02.007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16503127
Print-ISSN:
0959-437X
TUM Einrichtung:
Klinik und Poliklinik für Nuklearmedizin
 BibTeX