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Title:

Combined administration of nitric oxide gas and iloprost during cardiopulmonary bypass reduces platelet dysfunction: a pilot clinical study.

Document type:
Clinical Trial; Journal Article; Randomized Controlled Trial
Author(s):
Chung, A; Wildhirt, SM; Wang, S; Koshal, A; Radomski, MW
Abstract:
BACKGROUND: Thrombocytopenia and platelet dysfunction are major mechanisms of cardiopulmonary bypass-induced postoperative hemorrhage. This study evaluated the effects of low amounts of nitric oxide, iloprost (prostacyclin analog), and their combination administered directly into the oxygenator on platelet function, platelet-leukocyte interactions, and postoperative blood loss in patients undergoing coronary artery bypass grafting. METHODS: Blood samples from 41 patients randomized to the contro...     »
Journal title abbreviation:
J Thorac Cardiovasc Surg
Year:
2005
Journal volume:
129
Journal issue:
4
Pages contribution:
782-90
Language:
eng
Fulltext / DOI:
doi:10.1016/j.jtcvs.2004.06.049
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15821644
Print-ISSN:
0022-5223
TUM Institution:
Klinik für Herz- und Gefäßchirurgie (Prof. Lange)
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