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Titel:

Plasminogen activator inhibitor-1 4G/5G polymorphism and efficacy of reperfusion therapy in acute myocardial infarction.

Dokumenttyp:
Journal Article; Randomized Controlled Trial; Article
Autor(en):
Sibbing, D; von Beckerath, O; von Beckerath, N; Koch, W; Mehilli, J; Schwaiger, M; Schömig, A; Kastrati, A
Abstract:
Plasminogen activator inhibitor-1 (PAI-1) plays a central role in the modulation of intravascular thrombosis and thrombolysis. The level of transcription and the plasma level of PAI-1 are in part determined by the 4G/5G polymorphism in the promoter region of the gene. In this study we investigate the effect of 4G/5G polymorphism on the efficacy of reperfusion therapy in acute myocardial infarction (AMI). Two hundred and ninety-three patients were enrolled in two randomized trials comparing stent...     »
Zeitschriftentitel:
Blood Coagul Fibrinolysis
Jahr:
2005
Band / Volume:
16
Heft / Issue:
7
Seitenangaben Beitrag:
511-5
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16175011
Print-ISSN:
0957-5235
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie); Klinik und Poliklinik für Nuklearmedizin
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