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Titel:

Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages.

Dokumenttyp:
Journal Article; Article
Autor(en):
Laugwitz, KL; Moretti, A; Lam, J; Gruber, P; Chen, Y; Woodard, S; Lin, LZ; Cai, CL; Lu, MM; Reth, M; Platoshyn, O; Yuan, JX; Evans, S; Chien, KR
Abstract:
The purification, renewal and differentiation of native cardiac progenitors would form a mechanistic underpinning for unravelling steps for cardiac cell lineage formation, and their links to forms of congenital and adult cardiac diseases. Until now there has been little evidence for native cardiac precursor cells in the postnatal heart. Herein, we report the identification of isl1+ cardiac progenitors in postnatal rat, mouse and human myocardium. A cardiac mesenchymal feeder layer allows renewal...     »
Zeitschriftentitel:
Nature
Jahr:
2005
Band / Volume:
433
Heft / Issue:
7026
Seitenangaben Beitrag:
647-53
Sprache:
eng
Volltext / DOI:
doi:10.1038/nature03215
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15703750
Print-ISSN:
0028-0836
TUM Einrichtung:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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