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Title:

High-dose cytarabine and mitoxantrone in consolidation therapy for acute promyelocytic leukemia

Document type:
Clinical Trial; Journal Article; Multicenter Study; Journal Article
Author(s):
Schlenk, RF; Germing, U; Hartmann, F; Glasmacher, A; Fischer, JT; Fuentes, FDY; Götze, K; Pralle, H; Nerl, C; Salwender, H; Grimminger, W; Petzer, A; Hensel, M; Benner, A; Zick, L; Döhner, K; Frohling, S; Döhner, H
Abstract:
The objective of our study was to evaluate high-dose cytarabine in consolidation therapy in patients with newly diagnosed acute promyelocytic leukemia (APL). Patients (age 16-60 years) received induction therapy according to the AIDA protocol (all-trans retinoic acid, idarubicin) followed by one cycle of ICE ( idarubicin, cytarabine, etoposide) and two cycles of HAM (cytarabine 3 g/m(2) q12h, days 1-3; mitoxantrone 10 mg/m(2), days 2 and 3). From 1995 to 2003, 82 patients were enrolled. In tota...     »
Journal title abbreviation:
Leukemia
Year:
2005
Journal volume:
19
Journal issue:
6
Pages contribution:
978-983
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15843821
Print-ISSN:
0887-6924
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)
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