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Titel:

CCR4-deficient mice show prolonged graft survival in a chronic cardiac transplant rejection model.

Dokumenttyp:
Journal Article
Autor(en):
Hüser, N; Tertilt, C; Gerauer, K; Maier, S; Traeger, T; Assfalg, V; Reiter, R; Heidecke, CD; Pfeffer, K
Abstract:
Chronic graft rejection mediated by cellular immune responses still poses a serious clinical problem in transplant surgery. Chemokines coordinate the recruitment of leukocytes in inflammatory and immune responses. Their precise functions in the rejection of allografts are still ill defined. This study investigates the role of chemokine receptor 4 (CCR4) in acute and chronic cardiac allograft rejection in mice. Allogeneic hearts were transplanted into CCR4 deficient (CCR4(-/-)) and control recipi...     »
Zeitschriftentitel:
Eur J Immunol
Jahr:
2005
Band / Volume:
35
Heft / Issue:
1
Seitenangaben Beitrag:
128-38
Sprache:
eng
Volltext / DOI:
doi:10.1002/eji.200324745
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15593118
Print-ISSN:
0014-2980
TUM Einrichtung:
Chirurgische Klinik und Poliklinik
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