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Dokumenttyp:
Journal Article; Article
Autor(en):
Anton, M; Wagner, B; Haubner, R; Bodenstein, C; Essien, BE; Bönisch, H; Schwaiger, M; Gansbacher, B; Weber, WA
Titel:
Use of the norepinephrine transporter as a reporter gene for non-invasive imaging of genetically modified cells.
Abstract:
BACKGROUND: The norepinephrine transporter (NET) is a high-affinity transporter for catecholamines. Its expression is almost exclusively restricted to the sympathetic nervous system. In this study we evaluated whether the NET can be used as a reporter gene for non-invasive imaging of genetically modified cells with radiolabeled probes. METHODS: Human A431, HT1080 and murine CMS-5 cells were retrovirally transduced with bovine NET cDNA. Transduced and parental cells were incubated in vitro with [...     »
Zeitschriftentitel:
J Gene Med
Jahr:
2004
Band / Volume:
6
Heft / Issue:
1
Seitenangaben Beitrag:
119-26
Sprache:
eng
Volltext / DOI:
doi:10.1002/jgm.472
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/14716684
Print-ISSN:
1099-498X
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung; Klinik und Poliklinik für Nuklearmedizin
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