User: Guest  Login
Title:

Forty years of clinical aprotinin use: A review of 124 hypersensitivity reactions

Document type:
Journal Article; Review; Review
Author(s):
Beierlein, W; Scheule, AM; Dietrich, W; Ziemer, G
Abstract:
Since its clinical introduction, the anaphylactic potential of aprotinin has been a major concern. World wide, its use is expanding so there is an increased chance that patients have reexposure from various sources. The risk of anaphylaxis is approximately 2.8% in reexposed patients. From 1963 to 2003, 124 cases of aprotinin-induced anaphylaxis were reported in 61 publications. Eleven patients died. The reexposure interval was less than 3 months in 72% (38 of 53 patients). This review looks at t...     »
Journal title abbreviation:
Ann Thorac Surg
Year:
2005
Journal volume:
79
Journal issue:
2
Pages contribution:
741-748
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15680884
Print-ISSN:
0003-4975
TUM Institution:
Klinik für Anästhesiologie
 BibTeX