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Titel:

Forty years of clinical aprotinin use: A review of 124 hypersensitivity reactions

Dokumenttyp:
Journal Article; Review; Review
Autor(en):
Beierlein, W; Scheule, AM; Dietrich, W; Ziemer, G
Abstract:
Since its clinical introduction, the anaphylactic potential of aprotinin has been a major concern. World wide, its use is expanding so there is an increased chance that patients have reexposure from various sources. The risk of anaphylaxis is approximately 2.8% in reexposed patients. From 1963 to 2003, 124 cases of aprotinin-induced anaphylaxis were reported in 61 publications. Eleven patients died. The reexposure interval was less than 3 months in 72% (38 of 53 patients). This review looks at t...     »
Zeitschriftentitel:
Ann Thorac Surg
Jahr:
2005
Band / Volume:
79
Heft / Issue:
2
Seitenangaben Beitrag:
741-748
Sprache:
eng
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15680884
Print-ISSN:
0003-4975
TUM Einrichtung:
Klinik für Anästhesiologie
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