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Title:

Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Nasir, MN; Abdullah, J; Habsah, M; Ghani, RI; Rammes, G
Abstract:
The asiatic acid, a triterpenoids isolated from Centella asiatica was used to delineate its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. This study is consistent with asiatic acid having an effect on AChE, a selective GABA(B) receptor agonist and no sedative effect on locomotor.
Journal title abbreviation:
Phytomedicine
Year:
2012
Journal volume:
19
Journal issue:
3-4
Pages contribution:
311-6
Language:
eng
Fulltext / DOI:
doi:10.1016/j.phymed.2011.10.004
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22112723
Print-ISSN:
0944-7113
TUM Institution:
Klinik für Anästhesiologie (DHM)
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