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Title:

Recent developments in potential anxiolytic agents targeting GABAA/BzR complex or the translocator protein (18kDa) (TSPO).

Document type:
Journal Article; Review
Author(s):
Nothdurfter, C; Rupprecht, R; Rammes, G
Abstract:
Anxiety disorders are frequent and disabling disorders. For short-term treatment, benzodiazepines are useful due to their rapid onset of anxiolytic action. However, these compounds have sedative properties and may induce tolerance, abuse liability and withdrawal symptoms. First-line choices for the long-term treatment are selective serotonin reuptake inhibitors or serotonin-norepinephrine reuptake inhibitors. The major disadvantage of these compounds is their delayed onset of action. It is obvio...     »
Journal title abbreviation:
Curr Top Med Chem
Year:
2012
Journal volume:
12
Journal issue:
4
Pages contribution:
360-70
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/22204486
Print-ISSN:
1568-0266
TUM Institution:
Klinik für Anästhesiologie (DHM)
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