Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity.

Dokumenttyp:: Journal Article; Research Support, Non-U.S. Gov't
Autor(en):: Nasir, MN; Abdullah, J; Habsah, M; Ghani, RI; Rammes, G
Titel:: Inhibitory effect of asiatic acid on acetylcholinesterase, excitatory post synaptic potential and locomotor activity.
Abstract:: The asiatic acid, a triterpenoids isolated from Centella asiatica was used to delineate its inhibitory effect on acetylcholinesterase (AChE) properties, excitatory post synaptic potential (EPSP) and locomotor activity. This study is consistent with asiatic acid having an effect on AChE, a selective GABA(B) receptor agonist and no sedative effect on locomotor.
Zeitschriftentitel:: Phytomedicine
Jahr:: 2012
Band / Volume:: 19
Heft / Issue:: 3-4
Seitenangaben Beitrag:: 311-6
Sprache:: eng
Volltext / DOI:: doi:10.1016/j.phymed.2011.10.004
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/22112723
Print-ISSN:: 0944-7113
TUM Einrichtung:: Klinik für Anästhesiologie (DHM)
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