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Title:

Animal models of cardiopulmonary bypass: development, applications, and impact.

Document type:
Journal Article
Author(s):
Jungwirth, B; de Lange, F
Abstract:
Neurologic and neurocognitive complications after cardiac surgery have been reported repeatedly. To better understand its etiology and design protective strategies, small animal models have been developed. This study describes the development of a survival rat cardiopulmonary bypass (CPB) model, along with the introduction of an appropriately sized oxygenator. This model led the way for even more complicated models with CPB, facilitating full cardiac arrest with anterograde cardioplegia administ...     »
Journal title abbreviation:
Semin Cardiothorac Vasc Anesth
Year:
2010
Journal volume:
14
Journal issue:
2
Pages contribution:
136-40
Language:
eng
Fulltext / DOI:
doi:10.1177/1089253210370491
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/20478954
Print-ISSN:
1089-2532
TUM Institution:
Klinik für Anästhesiologie (DHM)
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