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Dokumenttyp:
Journal Article
Autor(en):
Rammes, G; Danysz, W; Parsons, CG
Titel:
Pharmacodynamics of memantine: an update.
Abstract:
Memantine received marketing authorization from the European Agency for the Evaluation of Medicinal Products (EMEA) for the treatment of moderately severe to severe Alzheimer s disease (AD) in Europe on 17(th) May 2002 and shortly thereafter was also approved by the FDA for use in the same indication in the USA. Memantine is a moderate affinity, uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist with strong voltage-dependency and fast kinetics. Due to this mechanism of action (MOA), t...     »
Zeitschriftentitel:
Curr Neuropharmacol
Jahr:
2008
Band / Volume:
6
Heft / Issue:
1
Seitenangaben Beitrag:
55-78
Sprache:
eng
Volltext / DOI:
doi:10.2174/157015908783769671
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19305788
Print-ISSN:
1570-159X
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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