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Titel:

Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice.

Dokumenttyp:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Marsch, R; Foeller, E; Rammes, G; Bunck, M; Kössl, M; Holsboer, F; Zieglgänsberger, W; Landgraf, R; Lutz, B; Wotjak, CT
Abstract:
The transient receptor potential vanilloid type 1 channel (TRPV1) (formerly called vanilloid receptor VR1) is known for its key role of functions in sensory nerves such as perception of inflammatory and thermal pain. Much less is known about the physiological significance of the TRPV1 expression in the brain. Here we demonstrate that TRPV1 knock-out mice (TRPV1-KO) show less anxiety-related behavior in the light-dark test and in the elevated plus maze than their wild-type littermates with no dif...     »
Zeitschriftentitel:
J Neurosci
Jahr:
2007
Band / Volume:
27
Heft / Issue:
4
Seitenangaben Beitrag:
832-9
Sprache:
eng
Volltext / DOI:
doi:10.1523/JNEUROSCI.3303-06.2007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17251423
Print-ISSN:
0270-6474
TUM Einrichtung:
Klinik für Anästhesiologie (DHM)
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