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Titel:

Tissue engineering of bone: effects of mechanical strain on osteoblastic cells in type I collagen matrices.

Dokumenttyp:
Evaluation Studies; Journal Article
Autor(en):
Ignatius, A; Blessing, H; Liedert, A; Schmidt, C; Neidlinger-Wilke, C; Kaspar, D; Friemert, B; Claes, L
Abstract:
The aim of the present study was to investigate the effect of cyclic uniaxial mechanical strain on a human osteoblastic precursor cell line (hFOB 1.19) in three-dimensional type I collagen matrices. Cell seeded collagen constructs were mechanically stretched by a daily application of cyclic uniaxial strain using a special motor-driven apparatus and compared to unstretched controls. Expression of genes involved in cell proliferation and osteoblastic differentiation as well as matrix production we...     »
Zeitschriftentitel:
Biomaterials
Jahr:
2005
Band / Volume:
26
Heft / Issue:
3
Seitenangaben Beitrag:
311-8
Volltext / DOI:
doi:10.1016/j.biomaterials.2004.02.045
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15262473
Print-ISSN:
0142-9612
TUM Einrichtung:
Klinik und Poliklinik für Unfallchirurgie
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