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Title:

Extracellular human thioredoxin-1 inhibits lipopolysaccharide-induced interleukin-1beta expression in human monocyte-derived macrophages.

Document type:
Journal Article; Article
Author(s):
Billiet, L; Furman, C; Larigauderie, G; Copin, C; Brand, K; Fruchart, JC; Rouis, M
Abstract:
Oxidative stress plays an important role in atherosclerotic vascular disease, and several recent studies were focused on thioredoxin-1 (Trx-1) and its potential protective role against oxidative stress. Since human monocyte-derived macrophages (HMDM) are important cells in several inflammatory diseases including atherosclerosis, we conducted this study to evaluate the impact of extracellular recombinant human Trx-1 (rhTrx-1) on gene expression in lipopolysaccharide-activated HMDM. Our results sh...     »
Journal title abbreviation:
J Biol Chem
Year:
2005
Journal volume:
280
Journal issue:
48
Pages contribution:
40310-8
Language:
eng
Fulltext / DOI:
doi:10.1074/jbc.M503644200
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/16207716
Print-ISSN:
0021-9258
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie
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