Valproate as an adjunct to antipsychotics for schizophrenia: a systematic review of randomized trials.

Document type:: Journal Article; Meta-Analysis; Review; Article
Author(s):: Basan, A; Kissling, W; Leucht, S
Title:: Valproate as an adjunct to antipsychotics for schizophrenia: a systematic review of randomized trials.
Abstract:: Randomized controlled trials comparing valproate (as a sole, or as an adjunctive compound) to placebo for patients with schizophrenia or schizophrenia-like disorders were summarized in a metaanalysis. It was possible to include only five trials (n = 379) examining valproate as add-on to antipsychotics in this review. Some of the single studies showed inconsistent beneficial effects on some aspects of response, but no overall superiority of valproate augmentation at study endpoints was shown.
Journal title abbreviation:: Schizophr Res
Year:: 2004
Journal volume:: 70
Journal issue:: 1
Pages contribution:: 33-7
Language:: eng
Fulltext / DOI:: doi:10.1016/j.schres.2004.01.016
Pubmed ID:: http://view.ncbi.nlm.nih.gov/pubmed/15246461
Print-ISSN:: 0920-9964
TUM Institution:: Klinik und Poliklinik für Psychiatrie und Psychotherapie
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