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Title:

Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala.

Document type:
Journal Article
Author(s):
Ranft, A; Kurz, J; Deuringer, M; Haseneder, R; Dodt, HU; Zieglgänsberger, W; Kochs, E; Eder, M; Hapfelmeier, G
Abstract:
Attempts have been made to attribute the particular features of general anaesthesia such as hypnosis, analgesia, amnesia and autonomic stability to certain brain regions. In the present study, we examined the effects of the commonplace volatile anaesthetic isoflurane on synaptic transmission in an in vitro slice preparation of the murine amygdala. Despite the established role of this limbic structure in the formation of aversive memories, conditioned fear and anxiety, as well as pain processing...     »
Journal title abbreviation:
Eur J Neurosci
Year:
2004
Journal volume:
20
Journal issue:
5
Pages contribution:
1276-80
Language:
eng
Fulltext / DOI:
doi:10.1111/j.1460-9568.2004.03603.x
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15341599
Print-ISSN:
0953-816X
TUM Institution:
Klinik für Anästhesiologie (DHM)
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