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Title:

Influence of propofol on neuronal damage and apoptotic factors after incomplete cerebral ischemia and reperfusion in rats: a long-term observation.

Document type:
Journal Article; Article
Author(s):
Engelhard, K; Werner, C; Eberspächer, E; Pape, M; Stegemann, U; Kellermann, K; Hollweck, R; Hutzler, P; Kochs, E
Abstract:
BACKGROUND: Propofol reduces neuronal damage from cerebral ischemia when investigated for less than 8 postischemic days. This study investigates the long-term effects of propofol on neuronal damage and apoptosis-related proteins after cerebral ischemia and reperfusion. METHODS: Male Sprague-Dawley rats were randomly assigned as follows: group 1 (n = 32, control): fentanyl and nitrous oxide-oxygen; group 2 (n = 32, propofol): propofol and oxygen-air. Ischemia (45 min) was induced by carotid arte...     »
Journal title abbreviation:
Anesthesiology
Year:
2004
Journal volume:
101
Journal issue:
4
Pages contribution:
912-7
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/15448524
Print-ISSN:
0003-3022
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie; Klinik für Anästhesiologie (DHM)
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