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Titel:

The highly conserved extracellular peptide, DSYG(893-896), is a critical structure for sodium pump function.

Dokumenttyp:
Journal Article
Autor(en):
Becker, S; Schneider, H; Scheiner-Bobis, G
Abstract:
The peptide sequence DSYG(893-896) of the sheep sodium pump alpha 1 subunit is highly conserved among all K(+)-transporting P-type ATPases. To obtain information about its function, single mutations were introduced and the mutants were expressed in yeast and analysed for enzymatic activity, ion recognition, and alpha/beta subunit interactions. Mutants of Ser894 or Tyr895 were all active. Conservative phenylalanine and tryptophan mutants of Tyr895 displayed properties that were similar to the pro...     »
Zeitschriftentitel:
Eur J Biochem
Jahr:
2004
Band / Volume:
271
Heft / Issue:
19
Seitenangaben Beitrag:
3821-31
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1432-1033.2004.04305.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/15373828
Print-ISSN:
0014-2956
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie
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