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Titel:

Role of the innate and adaptive immune responses in the course of multiple sclerosis.

Dokumenttyp:
Review; Review
Autor(en):
Hemmer, Bernhard; Kerschensteiner, Martin; Korn, Thomas
Abstract:
Multiple sclerosis is a chronic disease of the CNS that leads to substantial disability in most patients. The early phase is characterised by relapses and the later phase by progressive disability. Results from immunological, genetic, and histopathological studies and treatment trials have shown that the immune system plays a key part in the disease course. Findings from animal models and immunological studies of patients with multiple sclerosis suggest a change in the involvement of the immune...     »
Zeitschriftentitel:
Lancet Neurol
Jahr:
2015
Band / Volume:
14
Heft / Issue:
4
Seitenangaben Beitrag:
406-419
Sprache:
eng
Volltext / DOI:
doi:10.1016/S1474-4422(14)70305-9
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25792099
Print-ISSN:
1474-4422
TUM Einrichtung:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik
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