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Title:

Replacement of aprotinin by ?-aminocaproic acid in infants undergoing cardiac surgery: consequences for blood loss and outcome.

Document type:
Journal Article; Journal Article
Author(s):
Martin, K; Gertler, R; Macguill, M; Mayr, NP; Hapfelmeier, A; Hörer, J; Vogt, M; Tassani, P; Wiesner, G
Abstract:
Once aprotinin was no longer available for clinical use, ?-aminocaproic acid (EACA) and tranexamic acid became the only two options for antifibrinolytic therapy. We compared aprotinin and EACA with respect to their blood-sparing efficacy and other major clinical outcome criteria in infants undergoing cardiac surgery.We retrospectively analysed data from a large consecutive cohort of infants (n=227) aged 31-365 days undergoing primary cardiac surgery requiring cardiopulmonary bypass encompassing...     »
Journal title abbreviation:
Br J Anaesth
Year:
2013
Journal volume:
110
Journal issue:
4
Pages contribution:
615-21
Language:
eng
Fulltext / DOI:
doi:10.1093/bja/aes430
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/23213034
Print-ISSN:
0007-0912
TUM Institution:
Fachgebiet Kardioanästhesie (Prof. Tassani-Prell); Institut für Medizinische Statistik und Epidemiologie
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