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Titel:

Scaling of immune responses against intracellular bacterial infection.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Abdullah, Zeinab; Knolle, Percy A
Abstract:
Macrophages detect bacterial infection through pattern recognition receptors (PRRs) localized at the cell surface, in intracellular vesicles or in the cytosol. Discrimination of viable and virulent bacteria from non-virulent bacteria (dead or viable) is necessary to appropriately scale the anti-bacterial immune response. Such scaling of anti-bacterial immunity is necessary to control the infection, but also to avoid immunopathology or bacterial persistence. PRR-mediated detection of bacterial co...     »
Zeitschriftentitel:
EMBO J
Jahr:
2014
Band / Volume:
33
Heft / Issue:
20
Seitenangaben Beitrag:
2283-94
Sprache:
eng
Volltext / DOI:
doi:10.15252/embj.201489055
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25225613
Print-ISSN:
0261-4189
TUM Einrichtung:
Roman Herzog Comprehensive Cancer Center
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