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Titel:

Transfer of MHC-class-I molecules among liver sinusoidal cells facilitates hepatic immune surveillance.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Schölzel, Katrin; Schildberg, Frank A; Welz, Meike; Börner, Carolin; Geiger, Sergej; Kurts, Christian; Heikenwälder, Mathias; Knolle, Percy A; Wohlleber, Dirk
Abstract:
In the liver, antigen-presenting cell populations such as Kupffer cells, liver dendritic cells, and liver sinusoidal endothelial cells (LSECs) participate through cross-presentation to CD8 T cells (CTLs) in hepatic immune-regulation and immune-surveillance. The participation of hepatic stellate cells (HSCs) in immune regulation is controversial. Here we studied HSC's contribution to antiviral CTL immunity.Flow cytometric analysis of MHC-I molecules at the cell surface of liver cells from mice wi...     »
Zeitschriftentitel:
J Hepatol
Jahr:
2014
Band / Volume:
61
Heft / Issue:
3
Seitenangaben Beitrag:
600-8
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jhep.2014.04.028
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24798625
Print-ISSN:
0168-8278
TUM Einrichtung:
Institut für Virologie ; Roman Herzog Comprehensive Cancer Center
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