Benutzer: Gast  Login
Mehr Felder
Einfache Suche
Titel:

Circulating brain-derived neurotrophic factor concentrations and the risk of cardiovascular disease in the community.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Article
Autor(en):
Kaess, Bernhard M; Preis, Sarah R; Lieb, Wolfgang; Beiser, Alexa S; Yang, Qiong; Chen, Tai C; Hengstenberg, Christian; Erdmann, Jeanette; Schunkert, Heribert; Seshadri, Sudha; Vasan, Ramachandran S; Assimes, Themistocles L; Deloukas, Panos; Holm, Hilma; Kathiresan, Sekar; König, Inke R; McPherson, Ruth; Reilly, Muredach P; Roberts, Robert; Samani, Nilesh J; Stewart, Alexandre F R
Abstract:
Brain-derived neurotrophic factor (BDNF) is a pleiotropic peptide involved in maintaining endothelial integrity. It is unknown if circulating BDNF levels are associated with risk of cardiovascular disease (CVD).We prospectively investigated the association of circulating BDNF levels with cardiovascular events and mortality in 3687 participants (mean age 65 years, 2068 women) from the Framingham Heart Study (FHS). Using a common nonsynonomous single nucleotide polymorphism (SNP) in the BDNF gene...     »
Zeitschriftentitel:
J Am Heart Assoc
Jahr:
2015
Band / Volume:
4
Heft / Issue:
3
Seitenangaben Beitrag:
e001544
Sprache:
eng
Volltext / DOI:
doi:10.1161/JAHA.114.001544
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25762803
Print-ISSN:
2047-9980
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
 BibTeX