Benutzer: Gast  Login
Titel:

Drug-coated balloon therapy in coronary and peripheral artery disease.

Dokumenttyp:
Journal Article; Review
Autor(en):
Byrne, Robert A; Joner, Michael; Alfonso, Fernando; Kastrati, Adnan
Abstract:
Nonstent-based local drug delivery during percutaneous intervention offers potential for sustained antirestenotic efficacy without the limitations of permanent vascular implants. Preclinical studies have shown that effective local tissue concentrations of drugs can be achieved using drug-coated balloon (DCB) catheters. Matrix coatings consisting of a mixture of lipophilic paclitaxel and hydrophilic spacer (excipient) are most effective. Clinical applications most suited to DCB therapy are those...     »
Zeitschriftentitel:
Nat Rev Cardiol
Jahr:
2014
Band / Volume:
11
Heft / Issue:
1
Seitenangaben Beitrag:
13-23
Sprache:
eng
Volltext / DOI:
doi:10.1038/nrcardio.2013.165
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24189405
Print-ISSN:
1759-5002
TUM Einrichtung:
Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
 BibTeX