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- Title:
The Extracellular Matrix Metalloproteinase Inducer (EMMPRIN, CD147) - a potential novel target in atherothrombosis prevention?
- Document type:
- Journal Article; Review
- Author(s):
- Joghetaei, Nader; Stein, Andreas; Byrne, Robert A; Schulz, Christian; King, Lamin; May, Andreas E; Schmidt, Roland
- Abstract:
- The immunoglobulin superfamily member EMMPRIN (CD147) plays an important role in a number of organ systems, including the cardiovascular system. Here we review the contemporary understanding of EMMPRIN and EMMPRIN-associated sequelae in the course of atherosclerosis. A significant body of data documents the pivotal role of EMMPRIN in the complex processes of atherogenesis, atheroprogression, and acute atherosclerothrombosis, a role that goes beyond that of a mere marker of inflammation.
- Journal title abbreviation:
- Thromb Res
- Year:
- 2013
- Journal volume:
- 131
- Journal issue:
- 6
- Pages contribution:
- 474-80
- Language:
- eng
- Fulltext / DOI:
- doi:10.1016/j.thromres.2013.04.017
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/23669100
- Print-ISSN:
- 0049-3848
- TUM Institution:
- Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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