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Titel:

Enhanced pro-apoptotic activity of rituximab through IBTK silencing in non-Hodgkin lymphoma B-cells.

Dokumenttyp:
Journal Article
Autor(en):
Vecchio, Eleonora; Marino, Rossana; Mimmi, Selena; Canale, Camilla; Caiazza, Carmen; Arcucci, Alessandro; Ruocco, Maria Rosaria; Schiavone, Marco; Santamaria, Gianluca; Palmieri, Camillo; Iaccino, Enrico; Mallardo, Massimo; Quinto, Ileana; Fiume, Giuseppe
Abstract:
Rituximab is a commonly used chemotherapeutic drug for patients with aggressive lymphomas, such as non-Hodgkin's lymphoma (NHL). Currently, the combination of Rituximab and chemotherapy (R-CHOP) stands as the most prevalent first-line therapy for NHL. Nevertheless, the development of new therapeutic approaches remains imperative. An increasing body of evidence highlights a novel role for IBTK in tumorigenesis and cancer growth. In this study, we aim to broaden our understanding of IBTK's functio...     »
Zeitschriftentitel:
Front Oncol
Jahr:
2024
Band / Volume:
14
Volltext / DOI:
doi:10.3389/fonc.2024.1339584
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/38371626
Print-ISSN:
2234-943X
TUM Einrichtung:
Professur für Regenerative Medizin bei Kardiovaskulären Erkrankungen (Prof. Moretti)
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