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Titel:

ALDOC- and ENO2- driven glucose metabolism sustains 3D tumor spheroids growth regardless of nutrient environmental conditions: a multi-omics analysis.

Dokumenttyp:
Journal Article
Autor(en):
De Vitis, Claudia; Battaglia, Anna Martina; Pallocca, Matteo; Santamaria, Gianluca; Mimmi, Maria Chiara; Sacco, Alessandro; De Nicola, Francesca; Gaspari, Marco; Salvati, Valentina; Ascenzi, Francesca; Bruschini, Sara; Esposito, Antonella; Ricci, Giulia; Sperandio, Eleonora; Massacci, Alice; Prestagiacomo, Licia Elvira; Vecchione, Andrea; Ricci, Alberto; Sciacchitano, Salvatore; Salerno, Gerardo; French, Deborah; Aversa, Ilenia; Cereda, Cristina; Fanciulli, Maurizio; Chiaradonna, Ferdinando; Sol...     »
Abstract:
BACKGROUND: Metastases are the major cause of cancer-related morbidity and mortality. By the time cancer cells detach from their primary site to eventually spread to distant sites, they need to acquire the ability to survive in non-adherent conditions and to proliferate within a new microenvironment in spite of stressing conditions that may severely constrain the metastatic process. In this study, we gained insight into the molecular mechanisms allowing cancer cells to survive and proliferate in...     »
Zeitschriftentitel:
J Exp Clin Cancer Res
Jahr:
2023
Band / Volume:
42
Heft / Issue:
1
Volltext / DOI:
doi:10.1186/s13046-023-02641-0
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36945054
Print-ISSN:
0392-9078
TUM Einrichtung:
Professur für Regenerative Medizin bei Kardiovaskulären Erkrankungen (Prof. Moretti)
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