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Titel:

Intraindividual genome expression analysis reveals a specific molecular signature of psoriasis and eczema.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Quaranta, Maria; Knapp, Bettina; Garzorz, Natalie; Mattii, Martina; Pullabhatla, Venu; Pennino, Davide; Andres, Christian; Traidl-Hoffmann, Claudia; Cavani, Andrea; Theis, Fabian J; Ring, Johannes; Schmidt-Weber, Carsten B; Eyerich, Stefanie; Eyerich, Kilian
Abstract:
Previous attempts to gain insight into the pathogenesis of psoriasis and eczema by comparing their molecular signatures were hampered by the high interindividual variability of those complex diseases. In patients affected by both psoriasis and nonatopic or atopic eczema simultaneously (n = 24), an intraindividual comparison of the molecular signatures of psoriasis and eczema identified genes and signaling pathways regulated in common and exclusive for each disease across all patients. Psoriasis-...     »
Zeitschriftentitel:
Sci Transl Med
Jahr:
2014
Band / Volume:
6
Heft / Issue:
244
Seitenangaben Beitrag:
244ra90
Sprache:
eng
Volltext / DOI:
doi:10.1126/scitranslmed.3008946
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25009230
Print-ISSN:
1946-6234
TUM Einrichtung:
Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)
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