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- Document type:
- Journal Article; Article
- Author(s):
- Abri Aghdam, Kaveh; Reznicek, Lukas; Soltan Sanjari, Mostafa; Framme, Carsten; Bajor, Anna; Klingenstein, Annemarie; Kernt, Marcus; Seidensticker, Florian
- Title:
- Peripheral retinal non-perfusion and treatment response in branch retinal vein occlusion.
- Abstract:
- To evaluate the association between the size of peripheral retinal non-perfusion and the number of intravitreal ranibizumab injections in patients with treatment-naive branch retinal vein occlusion (BRVO) and macular edema.A total of 53 patients with treatment-naive BRVO and macular edema were included. Each patient underwent a full ophthalmologic examination including optical coherence tomography (OCT) imaging and ultra wide-field fluorescein angiography (UWFA). Monthly intravitreal ranibizumab injections were applied according to the recommendations of the German Ophthalmological Society. Two independent, masked graders quantified the areas of peripheral retinal non-perfusion.Intravitreal injections improved best-corrected visual acuity (BCVA) significantly from 22.23±16.33 Early Treatment of Diabetic Retinopathy Study (ETDRS) letters to 36.23±15.19 letters (P<0.001), and mean central subfield thickness significantly reduced from 387±115 µm to 321±115 µm (P=0.01). Mean number of intravitreal ranibizumab injections was 3.61±1.56. The size of retinal non-perfusion correlated significantly with the number of intravitreal ranibizumab injections (R=0.724, P<0.001).Peripheral retinal non-perfusion in patients with BRVO associates significantly with intravitreal ranibizumab injections in patients with BRVO and macular edema.
- Journal title abbreviation:
- Int J Ophthalmol
- Year:
- 2016
- Journal volume:
- 9
- Journal issue:
- 6
- Pages contribution:
- 858-62
- Language:
- eng
- Fulltext / DOI:
- doi:10.18240/ijo.2016.06.12
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/27366688
- Print-ISSN:
- 2222-3959
- TUM Institution:
- Klinik und Poliklinik für Augenheilkunde
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