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Titel:

Lifestyle intervention in BRCA1/2 mutation carriers: study protocol for a prospective, randomized, controlled clinical feasibility trial (LIBRE-1 study).

Dokumenttyp:
Journal Article
Autor(en):
Kiechle, Marion; Engel, Christoph; Berling, Anika; Hebestreit, Katrin; Bischoff, Stephan; Dukatz, Ricarda; Gerber, Wolf-Dieter; Siniatchkin, Michael; Pfeifer, Katharina; Grill, Sabine; Yahiaoui-Doktor, Maryam; Kirsch, Ellen; Niederberger, Uwe; Marter, Nicole; Enders, Ute; Löffler, Markus; Meindl, Alfons; Rhiem, Kerstin; Schmutzler, Rita; Erickson, Nicole; Halle, Martin
Abstract:
Women with highly penetrant BRCA mutations have a 55-60% lifetime risk for breast cancer and a 16-59% lifetime risk for ovarian cancer. However, penetrance differs interindividually, indicating that environmental and behavioral factors may modify this risk. These include lifestyle factors such as physical activity status, dietary habits, and body weight. The modification of penetrance by changing lifestyle factors has not thus far been investigated in a randomized trial in BRCA mutation carriers...     »
Zeitschriftentitel:
Pilot Feasibility Stud
Jahr:
2016
Band / Volume:
2
Seitenangaben Beitrag:
74
Sprache:
eng
Volltext / DOI:
doi:10.1186/s40814-016-0114-7
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/28031860
Print-ISSN:
2055-5784
TUM Einrichtung:
Poliklinik für Präventive und Rehabilitative Sportmedizin
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