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Title:

Hypoxic pre-conditioning increases the infiltration of endothelial cells into scaffolds for dermal regeneration pre-seeded with mesenchymal stem cells.

Document type:
Journal Article
Author(s):
Fierro, Fernando A; O'Neal, Adam J; Beegle, Julie R; Chávez, Myra N; Peavy, Thomas R; Isseroff, Roslyn R; Egaña, Jose T
Abstract:
Many therapies using mesenchymal stem cells (MSC) rely on their ability to produce and release paracrine signals with chemotactic and pro-angiogenic activity. These characteristics, however, are mostly studied under standard in vitro culture conditions. In contrast, various novel cell-based therapies imply pre-seeding MSC into bio-artificial scaffolds. Here we describe human bone marrow-derived MSC seeded in Integra matrices, a common type of scaffold for dermal regeneration (SDR). We show and m...     »
Journal title abbreviation:
Front Cell Dev Biol
Year:
2015
Journal volume:
3
Pages contribution:
68
Language:
eng
Fulltext / DOI:
doi:10.3389/fcell.2015.00068
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26579521
TUM Institution:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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