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Titel:

The Fibrin Matrix Regulates Angiogenic Responses within the Hemostatic Microenvironment through Biochemical Control.

Dokumenttyp:
Journal Article
Autor(en):
Hadjipanayi, Ektoras; Kuhn, Peer-Hendrik; Moog, Philipp; Bauer, Anna-Theresa; Kuekrek, Haydar; Mirzoyan, Lilit; Hummel, Anja; Kirchhoff, Katharina; Salgin, Burak; Isenburg, Sarah; Dornseifer, Ulf; Ninkovic, Milomir; Machens, Hans-Günther; Schilling, Arndt F
Abstract:
Conceptually, premature initiation of post-wound angiogenesis could interfere with hemostasis, as it relies on fibrinolysis. The mechanisms facilitating orchestration of these events remain poorly understood, however, likely due to limitations in discerning the individual contribution of cells and extracellular matrix. Here, we designed an in vitro Hemostatic-Components-Model (HCM) to investigate the role of the fibrin matrix as protein factor-carrier, independent of its cell-scaffold function....     »
Zeitschriftentitel:
PLoS ONE
Jahr:
2015
Band / Volume:
10
Heft / Issue:
8
Seitenangaben Beitrag:
e0135618
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.pone.0135618
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26317771
Print-ISSN:
1932-6203
TUM Einrichtung:
Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)
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