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Title:

Bisphosphonate and Medication-Related Osteonecrosis of the Jaw: A Review.

Document type:
Journal Article
Author(s):
Mücke, Thomas; Krestan, Christian R; Mitchell, David A; Kirschke, Jan S; Wutzl, Arno
Abstract:
For patients with malignant disease taking bisphosphonates and denosumab, the incidence of medication-related osteonecrosis of the jaw (MRONJ) is up to 15% in contrast to 0.01% in patients with osteoporosis. Clinical presentation of MRONJ extends from asymptomatic exposure of bone in 94% of patients to severe cases of mandibular fractures in a minority of 4.5%. The strongest risk factors for MRONJ are invasive dental procedures and dental infections. Advances in imaging provide more preoperation...     »
Journal title abbreviation:
Semin Musculoskelet Radiol
Year:
2016
Journal volume:
20
Journal issue:
3
Pages contribution:
305-314
Language:
eng
Fulltext / DOI:
doi:10.1055/s-0036-1592367
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27741546
Print-ISSN:
1089-7860
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
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