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Titel:

Redox regulation of genome stability by effects on gene expression, epigenetic pathways and DNA damage/repair.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Mikhed, Yuliya; Görlach, Agnes; Knaus, Ulla G; Daiber, Andreas
Abstract:
Reactive oxygen and nitrogen species (e.g. H2O2, nitric oxide) confer redox regulation of essential cellular signaling pathways such as cell differentiation, proliferation, migration and apoptosis. In addition, classical regulation of gene expression or activity, including gene transcription to RNA followed by translation to the protein level, by transcription factors (e.g. NF-?B, HIF-1?) and mRNA binding proteins (e.g. GAPDH, HuR) is subject to redox regulation. This review will give an update...     »
Zeitschriftentitel:
Redox Biol
Jahr:
2015
Band / Volume:
5
Seitenangaben Beitrag:
275-89
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.redox.2015.05.008
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26079210
TUM Einrichtung:
Klinik für Kinderkardiologie und angeborene Herzfehler (Prof. Hess)
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