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Titel:

Minimal residual disease detection in autologous stem cell grafts from patients with high risk neuroblastoma.

Dokumenttyp:
journal article
Autor(en):
van Wezel, Esther M; Stutterheim, Janine; Vree, Florentien; Zappeij-Kannegieter, Lily; Decarolis, Boris; Hero, Barbara; Berthold, Frank; Schumacher-Kuckelkorn, Roswitha; Simon, Thorsten; Fiocco, Marta; Voermans, Carlijn; van Noesel, Max M; Caron, Huib N; van der Schoot, C Ellen; Tytgat, Godelieve A M; GPOH MRD Study Group; Koehl, Ulrike; Schulte, Johannes H; Niggli, Felix; Fruhwald, Michael C; Niemeyer, Charlotte M; Bode, Udo; Schilling, Freimat H; Schultz, Christian; Graf, Norbert; Nathrath, Mi...     »
Abstract:
The clinical significance of minimal residual disease (MRD) detected by real-time quantitative PCR (qPCR) in autologous stem cell grafts in high risk neuroblastoma is still controversial. In this retrospective multicenter study, autologous stem cell grafts of a large cohort were studied using a panel of RNA markers.From 104 patients with high risk neuroblastoma, who received autologous stem cell transplantation as first line treatment, 66 peripheral blood stem cells (PBSC) and 38 CD34+ selected...     »
Zeitschriftentitel:
Pediatr Blood Cancer
Jahr:
2015
Band / Volume:
62
Heft / Issue:
8
Seitenangaben Beitrag:
1368-73
Sprache:
eng
Volltext / DOI:
doi:10.1002/pbc.25507
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25939774
Print-ISSN:
1545-5009
TUM Einrichtung:
Kinderklinik und Poliklinik
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