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Titel:

Neutrophils: Between host defence, immune modulation, and tissue injury.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Autor(en):
Kruger, Philipp; Saffarzadeh, Mona; Weber, Alexander N R; Rieber, Nikolaus; Radsak, Markus; von Bernuth, Horst; Benarafa, Charaf; Roos, Dirk; Skokowa, Julia; Hartl, Dominik
Abstract:
Neutrophils, the most abundant human immune cells, are rapidly recruited to sites of infection, where they fulfill their life-saving antimicrobial functions. While traditionally regarded as short-lived phagocytes, recent findings on long-term survival, neutrophil extracellular trap (NET) formation, heterogeneity and plasticity, suppressive functions, and tissue injury have expanded our understanding of their diverse role in infection and inflammation. This review summarises our current understan...     »
Zeitschriftentitel:
PLoS Pathog
Jahr:
2015
Band / Volume:
11
Heft / Issue:
3
Seitenangaben Beitrag:
e1004651
Sprache:
eng
Volltext / DOI:
doi:10.1371/journal.ppat.1004651
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25764063
Print-ISSN:
1553-7366
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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