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Titel:

Malignancy-associated haemophagocytic lymphohistiocytosis in children and adolescents.

Dokumenttyp:
Clinical Trial; Journal Article; Multicenter Study; Article
Autor(en):
Lehmberg, Kai; Sprekels, Björn; Nichols, Kim E; Woessmann, Wilhelm; Müller, Ingo; Suttorp, Meinolf; Bernig, Toralf; Beutel, Karin; Bode, Sebastian F N; Kentouche, Karim; Kolb, Reinhard; Längler, Alfred; Minkov, Milen; Schilling, Freimut H; Schmid, Irene; Vieth, Simon; Ehl, Stephan; zur Stadt, Udo; Janka, Gritta E
Abstract:
Haemophagocytic lymphohistiocytosis (HLH) in the context of malignancy is mainly considered a challenge of adult haematology. While this association is also observed in children, little is known regarding inciting factors, appropriate treatment and prognosis. We retrospectively analysed 29 paediatric and adolescent patients for presenting features, type of neoplasm or preceding chemotherapy, treatment and outcome. Haemophagocytic lymphohistiocytosis was considered triggered by the malignancy (M-...     »
Zeitschriftentitel:
Br J Haematol
Jahr:
2015
Band / Volume:
170
Heft / Issue:
4
Seitenangaben Beitrag:
539-49
Sprache:
eng
Volltext / DOI:
doi:10.1111/bjh.13462
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25940575
Print-ISSN:
0007-1048
TUM Einrichtung:
Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin
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