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Titel:

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate.

Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Article
Autor(en):
Foryst-Ludwig, Anna; Kreissl, Michael C; Benz, Verena; Brix, Sarah; Smeir, Elia; Ban, Zsofia; Januszewicz, El?bieta; Salatzki, Janek; Grune, Jana; Schwanstecher, Anne-Kathrin; Blumrich, Annelie; Schirbel, Andreas; Klopfleisch, Robert; Rothe, Michael; Blume, Katharina; Halle, Martin; Wolfarth, Bernd; Kershaw, Erin E; Kintscher, Ulrich
Abstract:
Endurance exercise training induces substantial adaptive cardiac modifications such as left ventricular hypertrophy (LVH). Simultaneously to the development of LVH, adipose tissue (AT) lipolysis becomes elevated upon endurance training to cope with enhanced energy demands. In this study, we investigated the impact of adipose tissue lipolysis on the development of exercise-induced cardiac hypertrophy. Mice deficient for adipose triglyceride lipase (Atgl) in AT (atATGL-KO) were challenged with chr...     »
Zeitschriftentitel:
J Biol Chem
Jahr:
2015
Band / Volume:
290
Heft / Issue:
39
Seitenangaben Beitrag:
23603-15
Sprache:
eng
Volltext / DOI:
doi:10.1074/jbc.M115.645341
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26260790
Print-ISSN:
0021-9258
TUM Einrichtung:
Poliklinik für Präventive und Rehabilitative Sportmedizin
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