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Title:

Elevated HbA1c is associated with increased risk of incident dementia in primary care patients.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Journal Article
Author(s):
Ramirez, Alfredo; Wolfsgruber, Steffen; Lange, Carolin; Kaduszkiewicz, Hanna; Weyerer, Siegfried; Werle, Jochen; Pentzek, Michael; Fuchs, Angela; Riedel-Heller, Steffi G; Luck, Tobias; Mösch, Edelgard; Bickel, Horst; Wiese, Birgitt; Prokein, Jana; König, Hans-Helmut; Brettschneider, Christian; Breteler, Monique M; Maier, Wolfgang; Jessen, Frank; Scherer, Martin
Abstract:
Type 2 diabetes mellitus (T2DM) is a risk factor of dementia. The effect of T2DM treatment quality on dementia risk, however, is unclear. 1,342 elderly individuals recruited via general practitioner registries (AgeCoDe cohort) were analyzed. This study analyzed the association between HbA1c level and the incidence of all-cause dementia (ACD) and of Alzheimer's disease dementia (referred to here as AD). HbA1c levels >=6.5% were associated with 2.8-fold increased risk of incident ACD (p = 0.027) a...     »
Journal title abbreviation:
J Alzheimers Dis
Year:
2015
Journal volume:
44
Journal issue:
4
Pages contribution:
1203-12
Language:
eng
Fulltext / DOI:
doi:10.3233/JAD-141521
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25524954
Print-ISSN:
1387-2877
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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