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Titel:

Link between hippocampus' raised local and eased global intrinsic connectivity in AD.

Dokumenttyp:
Journal Article; Article
Autor(en):
Pasquini, Lorenzo; Scherr, Martin; Tahmasian, Masoud; Meng, Chun; Myers, Nicholas E; Ortner, Marion; Mühlau, Mark; Kurz, Alexander; Förstl, Hans; Zimmer, Claus; Grimmer, Timo; Wohlschläger, Afra M; Riedl, Valentin; Sorg, Christian
Abstract:
The hippocampus (HP) is part of the default mode network (DMN), and both are key targets of Alzheimer's disease (AD). Because of widespread network degeneration, it has been suggested that increasing HP disconnection from the DMN may lead to progressive disinhibition of intra-HP synchronized activity.To analyze HP local (i.e., within HP) and global (i.e., within DMN) intrinsic functional connectivity (local/global intrinsic functional connectivity [iFC]), healthy controls and patients with mild...     »
Zeitschriftentitel:
Alzheimers Dement
Jahr:
2015
Band / Volume:
11
Heft / Issue:
5
Seitenangaben Beitrag:
475-84
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.jalz.2014.02.007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/25043909
Print-ISSN:
1552-5260
TUM Einrichtung:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Nuklearmedizin; Klinik und Poliklinik für Psychiatrie und Psychotherapie; Neurologische Klinik und Poliklinik
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