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Title:

Reduction of Amyloid-? Plasma Levels by Hemodialysis: An Anti-Amyloid Treatment Strategy?

Document type:
journal article
Author(s):
Tholen, Susanne; Schmaderer, Christoph; Chmielewski, Stefan; Förstl, Hans; Heemann, Uwe; Baumann, Marcus; Steubl, Dominik; Grimmer, Timo
Abstract:
Cognitive impairment in hemodialysis patients is common, but the underlying pathogenesis remains unclear. Alzheimer's disease is the most common cause of dementia in the general elderly population. Histopathological hallmarks are, among others, senile plaques, which consist of amyloid-? (A?).To measure plasma levels of A?42 and A?40 during hemodialysis and to examine potential associations with cognitive performance in cognitively impaired hemodialysis patients.Plasma samples of 26 hemodialysis...     »
Journal title abbreviation:
J Alzheimers Dis
Year:
2015
Journal volume:
50
Journal issue:
3
Pages contribution:
791-6
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26682683
Print-ISSN:
1387-2877
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie
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