User: Guest  Login
More Searchfields
Simple search
Title:

Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Brauchle, Eva; Knopf, Anne; Bauer, Hannah; Shen, Nian; Linder, Sandra; Monaghan, Michael G; Ellwanger, Kornelia; Layland, Shannon L; Brucker, Sara Y; Nsair, Ali; Schenke-Layland, Katja
Abstract:
One major obstacle to the application of stem cell-derived cardiomyocytes (CMs) for disease modeling and clinical therapies is the inability to identify the developmental stage of these cells without the need for genetic manipulation or utilization of exogenous markers. In this study, we demonstrate that Raman microspectroscopy can non-invasively identify embryonic stem cell (ESC)-derived chamber-specific CMs and monitor cell maturation. Using this marker-free approach, Raman peaks were identifi...     »
Journal title abbreviation:
Stem Cell Reports
Year:
2016
Journal volume:
6
Journal issue:
2
Pages contribution:
188-99
Language:
eng
Fulltext / DOI:
doi:10.1016/j.stemcr.2015.12.007
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26777059
TUM Institution:
Hals-Nasen-Ohrenklinik und Poliklinik
 BibTeX