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Titel:

Nanofiltrated C1-esterase-inhibitor in the prophylactic treatment of bradykinin-mediated angioedema.

Dokumenttyp:
Journal Article; Article
Autor(en):
Greve, Jens; Hahn, Janina; Nordmann, Melanie; Schuler, Patrick J; Bas, Murat; Hoffmann, Thomas K; Hajdu, Zuzana; Buchberger, Maria; Strassen, Ulrich
Abstract:
Patients suffering from bradykinin-induced angioedema show recurrent swelling of subcutaneous and submucosal structures. Increased bradykinin levels lead to an increase in vascular permeability and edema formation. Current therapy consists of B2 bradykinin receptor antagonists, C1-esterase-inhibitor (C1-INH) concentrate, or the kallikrein inhibitor ecallantide. In most cases the treatment of acute attacks is sufficient. Prophylactic therapy is recommended only in severe cases. C1-INHc has been s...     »
Zeitschriftentitel:
Transfusion
Jahr:
2016
Band / Volume:
56
Heft / Issue:
5
Seitenangaben Beitrag:
1022-9
Sprache:
eng
Volltext / DOI:
doi:10.1111/trf.13462
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26756974
Print-ISSN:
0041-1132
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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