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Titel:

An expression analysis of markers of radiation-induced skin fibrosis and angiogenesis in wound healing disorders of the head and neck.

Dokumenttyp:
Journal Article; Article
Autor(en):
Koerdt, Steffen; Rohleder, Nils H; Rommel, Niklas; Nobis, Christopher; Stoeckelhuber, Mechthild; Pigorsch, Steffi; Duma, Marciana-Nona; Wolff, Klaus-Dietrich; Kesting, Marco R
Abstract:
Radiation-induced fibrosis (RIF) is one of the severe long-term side effects of radiation therapy (RT) with a crucial impact on the development of postoperative wound healing disorders (WHD). The grades of fibrosis vary between mild to severe depending on individual radiosensitivity. In this study, we have investigated the molecular pathways that influence RIF and have correlated data from immunohistochemistry (IHC) for von -Willebrand Factor (vWF) and from Real-Time Polymerase Chain Reaction (R...     »
Zeitschriftentitel:
Radiat Oncol
Jahr:
2015
Band / Volume:
10
Heft / Issue:
1
Seitenangaben Beitrag:
202
Sprache:
eng
Volltext / DOI:
doi:10.1186/s13014-015-0508-3
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26390925
Print-ISSN:
1748-717X
TUM Einrichtung:
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie
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