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Titel:

Mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus: therapeutic and evolutionary implications.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Neubauer, Michael; Zhu, Zhaojun; Penka, Mirjam; Helmschrott, Christoph; Wagener, Nikola; Wagener, Johannes
Abstract:
Mitochondria within eukaryotic cells continuously fuse and divide. This phenomenon is called mitochondrial dynamics and crucial for mitochondrial function and integrity. We performed a comprehensive analysis of mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus. Phenotypic characterization of respective mutants revealed the general essentiality of mitochondrial fusion for mitochondrial genome maintenance and the mold's viability. Surprisingly, it turned out that the mitochondria...     »
Zeitschriftentitel:
Mol Microbiol
Jahr:
2015
Band / Volume:
98
Heft / Issue:
5
Seitenangaben Beitrag:
930-45
Sprache:
eng
Volltext / DOI:
doi:10.1111/mmi.13167
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26272083
Print-ISSN:
0950-382X
TUM Einrichtung:
Hals-Nasen-Ohrenklinik und Poliklinik
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