User: Guest  Login
Title:

Low-dose fludarabine with or without darbepoetin alfa in patients with chronic lymphocytic leukemia and comorbidity: primary results of the CLL9 trial of the German CLL Study Group.

Document type:
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Article
Author(s):
Goede, Valentin; Busch, Raymonde; Bahlo, Jasmin; Chataline, Viktoria; Kremers, Stephan; Müller, Lothar; Reschke, Daniel; Schlag, Rudolf; Schmidt, Burkhard; Vehling-Kaiser, Ursula; Wedding, Ulrich; Stilgenbauer, Stefan; Hallek, Michael
Abstract:
This study was planned as a phase 3 trial to investigate low-dose fludarabine with or without darbepoetin alfa in older patients with previously untreated or treated chronic lymphocytic leukemia (CLL) and comorbidity. Due to slow recruitment, the study was terminated prematurely after accrual of 97 patients who, on average, were 74 years old and had a cumulative illness rating scale (CIRS) total score of 5. We report toxicity and efficacy of the study treatment. Grade 3-5 neutropenia and infecti...     »
Journal title abbreviation:
Leuk Lymphoma
Year:
2016
Journal volume:
57
Journal issue:
3
Pages contribution:
596-603
Language:
eng
Fulltext / DOI:
doi:10.3109/10428194.2015.1079314
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/26293380
Print-ISSN:
1042-8194
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie
 BibTeX