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Title:

Robust Detection of Impaired Resting State Functional Connectivity Networks in Alzheimer's Disease Using Elastic Net Regularized Regression.

Document type:
Journal Article; Article
Author(s):
Teipel, Stefan J; Grothe, Michel J; Metzger, Coraline D; Grimmer, Timo; Sorg, Christian; Ewers, Michael; Franzmeier, Nicolai; Meisenzahl, Eva; Klöppel, Stefan; Borchardt, Viola; Walter, Martin; Dyrba, Martin
Abstract:
The large number of multicollinear regional features that are provided by resting state (rs) fMRI data requires robust feature selection to uncover consistent networks of functional disconnection in Alzheimer's disease (AD). Here, we compared elastic net regularized and classical stepwise logistic regression in respect to consistency of feature selection and diagnostic accuracy using rs-fMRI data from four centers of the "German resting-state initiative for diagnostic biomarkers" (psymri.org), c...     »
Journal title abbreviation:
Front Aging Neurosci
Year:
2016
Journal volume:
8
Pages contribution:
318
Language:
eng
Fulltext / DOI:
doi:10.3389/fnagi.2016.00318
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/28101051
TUM Institution:
Fachgebiet Neuroradiologie (Prof. Zimmer); Klinik und Poliklinik für Psychiatrie und Psychotherapie
 BibTeX